GOTOSEE.UK.COM
Sept. 7, 2008
A woman in the US who struggled to get pregnant with her first child and miscarried with a second pregnancy entered a study into acupuncture on polycystic ovary syndrome and fell pregnant
Rebecca Killmeyer claimed that acupuncture treatment helped her to ovulate regularly which in turn allowed her to become pregnant.
The study into acupuncture’s effects on polycystic ovary syndrome was carried out at UVA Health System and principle researcher Professor Lisa Pastore believes acupuncture could be an important alternative, non-drug therapy for women with the disorder.
“Over the last year we have seen women who never had a regular menstrual cycle start having regular periods,” said Pastore.
“We can also boast several pregnancies since the study began. Now we would like to recruit more people to the study in order to complete it.
“It is important for research to have enough participants to ensure that the results are scientifically credible and not due to chance.”
Before entering into the program, Rebecca Killmeyer was sceptical but her concerns soon gave way to feelings of relaxation.
“When I saw those tiny little needles coming at me I thought to myself, ‘I didn’t sign up for this!’ but I tried it and after a few minutes I was asleep on the table,” Killmeyer said.
“The sessions were completely refreshing after awhile.”
Killmeyer developed polycystic ovary syndrome in 2005 and has not had regular, monthly periods in over five years. One month after she started acupuncture treatments she got a period and for the next three months, they continued.
While there are many traditional drugs and therapies that manage this syndrome, this research is assessing whether acupuncture can be successful in regulating hormones and curing the symptoms of polycystic ovary syndrome.
http://alternativemedicine-gotosee.blogspot.com/2008/09/women-with-polycystic-ovary-syndrome.html
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Waukee, IA
The Journal of Clinical Endocrinology & Metabolism Vol. 93, No. 7 2670-2678
Karen Elkind-Hirsch, Ory Marrioneaux, Madhu Bhushan, Denise Vernor and Rajat Bhushan
Woman’s Health Research Institute (K.E.-H.), Woman’s Hospital, and Metabolic Center of Louisiana Research Foundation (O.M., M.B., D.V., R.B.), Baton Rouge, Louisiana 70815
Context: Insulin resistance and obesity are common features of the polycystic ovary syndrome (PCOS). Weight loss and use of insulin-lowering drugs have been shown to improve both reproductive and metabolic aspects of PCOS.
Objective: We evaluated exenatide (EX) and metformin (MET), alone and in combination (COM), on menstrual cyclicity, hormonal parameters, metabolic profiles, and inflammatory markers in overweight, insulin-resistant women with PCOS.
Design, Setting, and Participants: Sixty overweight oligoovulatory women with PCOS (body mass index > 27; 18–40 yr) were randomized to one of three treatment groups: MET [1000 mg twice daily (BID)], EX (10 µg BID), or COM (MET 1000 mg BID, EX 10 µg BID) for 24 wk. The primary outcome was menstrual frequency; secondary outcome measures included changes in ovulation rate, insulin action, anthropometric measures, androgen levels, and inflammatory markers.
Results: Forty-two (70%) patients completed the study. COM therapy was superior to EX or MET monotherapy in improving menstrual cyclicity, ovulation rate, free androgen index, and insulin sensitivity measures and reducing weight and abdominal fat. Both EX arms were more effective in promoting weight loss than MET (P = 0.003).
Conclusions: COM appears better than either EX or MET alone on menstrual cycle frequency and hormonal and metabolic derangements. A marked decrease in central adiposity could partly explain the improvements in reproductive function, insulin-glucose parameters, and adiponectin observed in these overweight women with PCOS treated with COM therapy. Larger trials of longer duration are warranted to assess the long-term efficacy and safety of combined EX-MET therapy in overweight women with PCOS.
http://jcem.endojournals.org/cgi/content/abstract/93/7/2670
