Women with PCOS reduced weight with lifestyle modification

June 17th, 2008

Endocrine Today
June 16, 2008

The Endocrine Society’s 90th Annual Meeting

Adolescent women with obesity and polycystic ovary syndrome treated with oral contraceptives showed a reduction in weight with a lifestyle modification program, according to the results from a recent study.

Kathleen M. Hoeger, MD, associate professor, department of obstetrics and gynecology, Rochester, NY, presented the results of this randomized, placebo controlled trial today at The Endocrine Society’s 90th Annual Meeting, held in San Francisco.

The researchers examined the role of metformin on the metabolic impact of oral contraceptives in obese adolescents who were enrolled in a lifestyle modification program. They assigned 36 participants to an oral contraceptive (30 mcg ethinyl estradiol, 3.0 mg drosperinone) and either 2,000 mg/day of metformin or placebo, according to the study.

Metabolic syndrome was present in 30% of participants, and impaired glucose tolerance was present in 25% of participants; 70% of participants met lifestyle goals for weight loss and exercise.

Metabolic syndrome was present in 14% of the participants in the metformin group and in 15% of the placebo group, according to the study. Ferriman-Galway scores decreased by 32.3% in the metformin group (P=.002) and by 31% in the placebo group (P<.001). – by Christen Haigh

    For more information:

        * Hoeger KM, Kochman L, Cherry T, et al. OR28-6. A randomized, placebo controlled trial of metformin in combination with lifestyle modification in obese adolescent women with polycystic ovary syndrome (PCOS) treated with oral contraceptives. Presented at: The Endocrine Society’s 90th Annual Meeting; June 15-18; San Francisco.

 

One Response to “Women with PCOS reduced weight with lifestyle modification”

  1. Angi Ingalls Says:

    I felt compelled to come here and respond with some sort of disclaimer because not all the facts are given here.

    When given the options of taking birth control hormones, you must certainly look at all the risk factors. BCH’s increase the risk for cysts (which in turn increases androgen levels) and insulin response issues which directly compound PCOS for the worse.

    If you try to help repair some of the PCOS damage with life style changes and real protocols that have been proven to help PCOS at the core, then the weight should come off. Birth control hormones are not a “weight loss” pill; its a drug that directly affects PCOS … ultimately putting more hurdles in the way of symptom-repair.

    LINK: http://pcos.insulitelabs.com/blog/index.php/can-birth-control-pills-affect-pcos

    Angi Ingalls; PCOS in ConnecTion
    Guest PCOS writer
    pcosinct@yahoo.com
    Educator for over 18 years
    Diagnosed in 1985 at 12, living with PCOS since 1981

    DISCLAIMER: The information contained in this article and the Insulite Labs website is for the sole purpose of being informative. Information obtained is not and should not be used or relied upon as medical advice. Always seek the advice of your physician, nurse or other qualified health care provider before you undergo any treatment, take any medication, supplements or other nutritional support, or for answers to any questions you may have regarding a medical condition.

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